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AChRα3 rabbit pAb
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ES1582
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AChRα3 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human AChRalpha3. AA range:90-139
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 1136
Human Swiss-Prot No: P32297
Cellular localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein.
Background: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],