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HOME2 rabbit pAb
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ES15690
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50 µL $148.00
100 µL $248.00
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Overview

Product name: HOME2 rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: Homer protein homolog 2 (Homer-2) (Cupidin)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human HOME2 AA range: 17-67
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 9455
Human Swiss-Prot No: Q9NSB8
Cellular localization: Cytoplasm . Cell membrane . Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cell projection, stereocilium . Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.
Background: This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011],