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ABCC12 rabbit pAb
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ES1565
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ABCC12 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MRP9. AA range:691-740
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 170kD
GeneID: 94160
Human Swiss-Prot No: Q96J65
Cellular localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Background: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008],