Product name: |
INT7 rabbit pAb |
Reactivity: |
Human; Mouse |
Alternative Names: |
Integrator complex subunit 7 (Int7) |
Source: |
Rabbit |
Dilutions: |
WB 1:500-2000 |
Immunogen: |
Synthesized peptide derived from human INT7 AA range: 364-414 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
105kD |
GeneID: |
25896 |
Human Swiss-Prot No: |
Q9NVH2 |
Cellular localization: |
Nucleus . Chromosome . Cytoplasm . Localizes to sites of DNA damage in a H2AX-independent manner. |
Background: |
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010], |