Product name: |
ITK rabbit pAb |
Reactivity: |
Human; Mouse |
Alternative Names: |
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2;Interleukin-2-inducible T-cell kinase;IL-2-inducible T-cell kinase;Kinase EMT;T-cell-specific kinase;Tyrosine-protein kinase Lyk) |
Source: |
Rabbit |
Dilutions: |
IHC-p 1:50-200, WB 1:500-2000 |
Immunogen: |
Synthesized peptide derived from human ITK AA range: 450-530 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
72kD |
GeneID: |
3702 |
Human Swiss-Prot No: |
Q08881 |
Cellular localization: |
Cytoplasm . Nucleus . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation. |
Background: |
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008], |