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Jak3 (phospho-Tyr980/981) rabbit pAb
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ES15392
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Jak3 (phospho-Tyr980/981) rabbit pAb
Reactivity: Human;Mouse
Alternative Names: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized phosho peptide around human Jak3 (Tyr980 and 981)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 125kD
GeneID: 3718
Human Swiss-Prot No: P52333
Cellular localization: Endomembrane system ; Peripheral membrane protein . Cytoplasm .
Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],