Products

Tensin-1 (phospho Tyr1326) rabbit pAb
One-click to copy product information
ES1531
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Tensin-1 (phospho Tyr1326) rabbit pAb
Reactivity: Human;Mouse
Alternative Names: TNS1; TNS; Tensin-1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Tensin-1 (phospho Tyr1326)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 185kD
GeneID: 7145
Human Swiss-Prot No: Q9HBL0
Cellular localization: Cell surface . Cell junction, focal adhesion . Cytoplasm, cytoskeleton . Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
Background: The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],