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LONM rabbit pAb
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ES15134
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50 µL $148.00
100 µL $248.00
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Overview

Product name: LONM rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: Lon protease homolog, mitochondrial (EC 3.4.21.-) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human LONM AA range: 398-448
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 105kD
GeneID: 9361
Human Swiss-Prot No: P36776
Cellular localization: Mitochondrion matrix .
Background: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013],