LRRN2 rabbit pAb

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LRRN2 rabbit pAb

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ES15098

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	LRRN2 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	Synthesized peptide derived from human LRRN2 AA range: 296-346
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Molecular Weight:	78kD
GeneID:	10446
Human Swiss-Prot No:	O75325
Cellular localization:	Membrane ; Single-pass type I membrane protein .
Background:	The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],

Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).