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MARCKS (phospho-Ser159/163) rabbit pAb
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ES15034
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50 µL $148.00
100 µL $248.00
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Overview

Product name: MARCKS (phospho-Ser159/163) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Source: Rabbit
Dilutions: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human MARCKS (Ser159 and 163)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 32kD
GeneID: 4082
Human Swiss-Prot No: P29966
Cellular localization: Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .
Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],