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NDUFA1 Polyclona Antibody
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ES14533
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NDUFA1 Polyclona Antibody
Reactivity: Human; Mouse; Rat
Alternative Names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen: Synthesized peptide derived from human NDUFA1 AA range: 20-100
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 4694
Human Swiss-Prot No: O15239
Cellular localization: Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
Background: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],