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NEUR3 rabbit pAb
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ES14518
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NEUR3 rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human NEUR3 AA range: 132-182
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 47kD
Human Swiss-Prot No: Q9UQ49
Cellular localization: Cell membrane ; Peripheral membrane protein . Membrane, caveola . Early endosome membrane ; Peripheral membrane protein . Recycling endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Associates with the external leaflet of the plasma membrane (By similarity). S-acylated NEU3 likely spans the lipid bilayer with a portion of C-terminus exposed to the cytosol and the catalytic region facing the extracellular space (PubMed:28646141). .
Background: This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008],