Products

Nuclear Receptor NR4A1 (Phospho-Ser351) Antibody
One-click to copy product information
ES14439
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Nuclear Receptor NR4A1 (Phospho-Ser351) Antibody
Reactivity: Human; Mouse; Rat
Alternative Names: Nuclear receptor subfamily 4 group A member 1 (Early response protein NAK1;Nuclear hormone receptor NUR/77;Nur77;Orphan nuclear receptor HMR;Orphan nuclear receptor TR3;ST-59;Testicular receptor 3)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA(peptide)1:5000-20000
Immunogen: Synthesized pospho peptide derived from human Nuclear Receptor NR4A1 (Phospho-Ser351)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 77kD
GeneID: 3164
Human Swiss-Prot No: P22736
Cellular localization: Nucleus . Cytoplasm . Mitochondrion . Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). .
Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],