Products

P4HA1 rabbit pAb
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ES14319
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: P4HA1 rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human P4HA1 AA range: 461-511
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 59kD
GeneID: 5033
Human Swiss-Prot No: P13674
Cellular localization: Endoplasmic reticulum lumen.
Background: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],