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PARG rabbit pAb
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ES14260
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50 µL $148.00
100 µL $248.00
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Overview

Product name: PARG rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human PARG AA range: 140-190
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 107kD
GeneID: 8505
Human Swiss-Prot No: Q86W56
Cellular localization: [Isoform 1]: Nucleus . Colocalizes with PCNA at replication foci (PubMed:21398629). Relocalizes to the cytoplasm in response to DNA damage (PubMed:16460818). .; [Isoform 2]: Cytoplasm . Translocates to the nucleus in response to DNA damage. .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm . Mitochondrion .; [Isoform 5]: Mitochondrion matrix .
Background: This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],