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PDE4B rabbit pAb
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ES14187
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50 µL $148.00
100 µL $248.00
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Overview

Product name: PDE4B rabbit pAb
Reactivity: Human;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human PDE4B AA range: 103-153
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 81kD
GeneID: 5142
Human Swiss-Prot No: Q07343
Cellular localization: [Isoform PDE4B5]: Cytoplasm . Cell membrane .
Background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],