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PNK1 (phospho-Ser114/Thr118) rabbit pAb
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ES14048
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50 µL $148.00
100 µL $248.00
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Overview

Product name: PNK1 (phospho-Ser114/Thr118) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized phosho peptide around human PNK1 (Ser114 and Thr118)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 11284
Human Swiss-Prot No: Q96T60
Cellular localization: Nucleus . Chromosome . Localizes to site of double-strand breaks. .
Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010],