Product name: |
POLD4 Polyclona Antibody |
Reactivity: |
Human;Rat;Mouse; |
Alternative Names: |
DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12) |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Immunogen: |
Synthesized peptide derived from human POLD4 AA range: 43-93 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
GeneID: |
57804 |
Human Swiss-Prot No: |
Q9HCU8 |
Cellular localization: |
Nucleus . Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation. . |
Background: |
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012], |