Products

RAD1 rabbit pAb
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ES13476
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: RAD1 rabbit pAb
Reactivity: Human; Mouse
Alternative Names: Cell cycle checkpoint protein RAD1 (hRAD1;EC 3.1.11.2;DNA repair exonuclease rad1 homolog;Rad1-like DNA damage checkpoint protein)
Source: Rabbit
Dilutions: IHC-p 1:50-200, WB 1:500-2000
Immunogen: Synthesized peptide derived from human RAD1
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 32kD
GeneID: 5810
Human Swiss-Prot No: O60671
Cellular localization: Nucleus .
Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009],