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RSH4A rabbit pAb
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ES13330
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50 µL $148.00
100 µL $248.00
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Overview

Product name: RSH4A rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human RSH4A AA range: 287-337
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 79kD
GeneID: 345895
Human Swiss-Prot No: Q5TD94
Cellular localization: Cytoplasm, cytoskeleton, cilium axoneme . Cell projection, cilium . Radial spoke. .
Background: This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],