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RT4I1 rabbit pAb
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ES13321
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50 µL $148.00
100 µL $248.00
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Overview

Product name: RT4I1 rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human RT4I1 AA range: 282-332
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 44kD
GeneID: 84816
Human Swiss-Prot No: Q8WWV3
Cellular localization: Mitochondrion outer membrane . Colocalizes with the endoplasmic reticulum HSPA5 at spots corresponding to contacts with mitochondria. .
Background: This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],