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SH3G1 rabbit pAb
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ES13128
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SH3G1 rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human SH3G1 AA range: 112-162
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 40kD
GeneID: 6455
Human Swiss-Prot No: Q99961
Cellular localization: Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Cell projection, podosome . Associated with postsynaptic endosomes in hippocampal neurons. .
Background: This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],