SPP2A rabbit pAb

Products

SPP2A rabbit pAb

One-click to copy product information

ES12985

Size：	Price：
50 µL	$148.00
100 µL	$248.00

Manual Send email to us

Overview

Product name:	SPP2A rabbit pAb
Reactivity:	Human; Mouse
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from human SPP2A AA range: 66-116
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Molecular Weight:	57kD
GeneID:	84888
Human Swiss-Prot No:	Q8TCT8
Cellular localization:	Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein ; Lumenal side . Colocalizes with palmitoylated and myristoylated proteins at the plasma membrane.
Background:	This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012],

Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).