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STX5 rabbit pAb
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ES12888
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50 µL $148.00
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Overview

Product name: STX5 rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: Syntaxin-5
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human STX5 AA range: 233-283
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 6811
Human Swiss-Prot No: Q13190
Cellular localization: Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type IV membrane protein . Golgi apparatus membrane . Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. .
Background: This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],