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TIM50 rabbit pAb
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ES12695
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TIM50 rabbit pAb
Reactivity: Human; Mouse
Alternative Names: Mitochondrial import inner membrane translocase subunit TIM50
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human TIM50 AA range: 109-159
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 92609
Human Swiss-Prot No: Q3ZCQ8
Cellular localization: Mitochondrion inner membrane ; Single-pass membrane protein .; [Isoform 2]: Nucleus speckle . Nuclear and enriched in speckles with snRNPs. .
Background: This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016],