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TLE3 rabbit pAb
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ES12682
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TLE3 rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human TLE3 AA range: 257-307
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID: 7090
Human Swiss-Prot No: Q04726
Cellular localization: Nucleus.
Background: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],