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TORC1/CRTC1 (phospho-Ser151) rabbit pAb
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ES12606
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TORC1/CRTC1 (phospho-Ser151) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
Source: Rabbit
Dilutions: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID: 23373
Human Swiss-Prot No: Q6UUV9
Cellular localization: Cytoplasm . Nucleus . Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (PubMed:16817901). Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (PubMed:15589160). Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (By similarity). .