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TRI37 rabbit pAb
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ES12574
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TRI37 rabbit pAb
Reactivity: Human; Mouse
Alternative Names: E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human TRI37 AA range: 315-365
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 105kD
GeneID: 4591
Human Swiss-Prot No: O94972
Cellular localization: Cytoplasm, perinuclear region . Peroxisome . Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation. .
Background: This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016],