Products

TRPC6 rabbit pAb
One-click to copy product information
ES12548
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: TRPC6 rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1：500-2000
Immunogen: Synthesized peptide derived from human TRPC6 AA range: 412-462
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 102kD
GeneID: 7225
Human Swiss-Prot No: Q9Y210
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009],