$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | TTL rabbit pAb |
Reactivity: | Human; Mouse;Rat |
Source: | Rabbit |
Dilutions: | WB 1:500-2000 |
Immunogen: | Synthesized peptide derived from human TTL AA range: 160-210 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Molecular Weight: | 41kD |
GeneID: | 150465 |
Human Swiss-Prot No: | Q8NG68 |
Background: | TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008], |