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Tuberin/TSC2 (phospho-Ser664) rabbit pAb
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ES12496
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Tuberin/TSC2 (phospho-Ser664) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Tuberin (Tuberous sclerosis 2 protein)
Source: Rabbit
Dilutions: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human Tuberin (Ser664)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 200kD
GeneID: 7249
Human Swiss-Prot No: P49815
Cellular localization: Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],