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VPS45 rabbit pAb
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ES12347
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50 µL $148.00
100 µL $248.00
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Overview

Product name: VPS45 rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human VPS45 AA range: 470-520
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID: 11311
Human Swiss-Prot No: Q9NRW7
Cellular localization: Golgi apparatus membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Associated with Golgi/endosomal vesicles and the trans-Golgi network. .
Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],