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YMEL1 rabbit pAb
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ES12257
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50 µL $148.00
100 µL $248.00
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Overview

Product name: YMEL1 rabbit pAb
Reactivity: Human; Mouse;Rat
Alternative Names: ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human YMEL1 AA range: 136-186
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID: 10730
Human Swiss-Prot No: Q96TA2
Cellular localization: Mitochondrion inner membrane . Mitochondrion .
Background: The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],