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OCLN rabbit pAb
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ES11811
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50 µL $148.00
100 µL $248.00
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Overview

Product name: OCLN rabbit pAb
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilutions: WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Immunogen: Synthesized peptide derived from part region of human protein. AA350-400
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 100506658
Human Swiss-Prot No: Q16625
Cellular localization: Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction .
Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],