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CRM1 (Acetyl Lys568) rabbit pAb
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ES1133
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CRM1 (Acetyl Lys568) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 125kD
GeneID: 7514
Human Swiss-Prot No: O14980
Cellular localization: Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.
Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],