$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | PORIM rabbit pAb |
Reactivity: | Human;Rat;Mouse |
Source: | Rabbit |
Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
Immunogen: | Synthesized peptide derived from part region of human protein |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 22kD |
GeneID: | 114908 |
Human Swiss-Prot No: | Q8N131 |
Cellular localization: | Membrane ; Single-pass type I membrane protein . |
Background: | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008], |