Products

ADA22 rabbit pAb
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ES11016
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: ADA22 rabbit pAb
Reactivity: Human;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 99kD
GeneID: 53616
Human Swiss-Prot No: Q9P0K1
Cellular localization: Cell membrane ; Single-pass type I membrane protein . Cell projection, axon .
Background: ADAM metallopeptidase domain 22(ADAM22) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010],