Synthesized peptide derived from part region of human protein
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
81kD
GeneID:
92737
Human Swiss-Prot No:
Q8NFT8
Cellular localization:
Cell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). .
Background:
function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.,similarity:Contains 1 follistatin-like domain.,similarity:Contains 10 EGF-like domains.,subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.,subunit:Interacts with AP1G1. Interacts with NOTCH1.,tissue specificity:Expressed in brain, spinal cord and adrenal gland.,
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