Synthesized peptide derived from part region of human protein
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
74kD
GeneID:
114990
Human Swiss-Prot No:
Q6EMK4
Cellular localization:
Membrane ; Single-pass type I membrane protein . Secreted .
Background:
function:May act as an inhibitor of TGF-beta signaling.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Interacts with TGFB1, TGFB2 and TGFB3.,tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.,
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