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AMBP rabbit pAb
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ES10973
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AMBP rabbit pAb
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 259
Human Swiss-Prot No: P02760
Cellular localization: [Alpha-1-microglobulin]: Secreted . Endoplasmic reticulum . Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein . Nucleus membrane ; Peripheral membrane protein . Mitochondrion inner membrane ; Peripheral membrane protein . Secreted, extracellular space, extracellular matrix . The cellular uptake occurs via a non-endocytotic pathway and allows for localization to various membrane structures. A specific binding to plasma membrane suggests the presence of a cell receptor, yet to be identified. Directly binds collagen fibers type I. .
Background: This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008],