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SKAP1 rabbit pAb
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ES10947
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SKAP1 rabbit pAb
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 39kD
GeneID: 8631
Human Swiss-Prot No: Q86WV1
Cellular localization: Cytoplasm . Nucleus . Cell membrane . Upon T-cell stimulation, translocates to lipid rafts at the cell membrane. .
Background: This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008],