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OPT rabbit pAb
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ES10911
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50 µL $148.00
100 µL $248.00
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Overview

Product name: OPT rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 36kD
GeneID: 26254
Human Swiss-Prot No: Q9UBM4
Cellular localization: Secreted, extracellular space, extracellular matrix .
Background: Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008],