Products

TNR8 rabbit pAb
One-click to copy product information
ES10856
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: TNR8 rabbit pAb
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 IHC-p: 50-200 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID: 943
Human Swiss-Prot No: P28908
Cellular localization: [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm .
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],