Cleaved-Plasma Kallikrein HC (R390) rabbit pAb

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Cleaved-Plasma Kallikrein HC (R390) rabbit pAb

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ES1072

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Cleaved-Plasma Kallikrein HC (R390) rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	45kD
GeneID:	3818
Human Swiss-Prot No:	P03952
Cellular localization:	Secreted.
Background:	This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],

Western Blot analysis of various cells using Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody diluted at 1:1000
Western Blot analysis of HeLa cells using Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody diluted at 1:1000
Western blot analysis of lysates from HeLa cells, using KLKB1 (heavy chain,Cleaved-Arg390) Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).