ASPM rabbit pAb

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ASPM rabbit pAb

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ES10611

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	ASPM rabbit pAb
Reactivity:	Human;Rat;Mouse;
Source:	Rabbit
Dilutions:	IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from human protein . at AA range: 1230-1310
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	382kD
GeneID:	259266
Human Swiss-Prot No:	Q8IZT6
Cellular localization:	Cytoplasm . Cytoplasm, cytoskeleton, spindle . Nucleus . The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin (By similarity). Localizes to spindle poles during mitosis (PubMed:19690332). Associates with microtubule minus ends (By similarity). .
Background:	This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011],

Immunohistochemical analysis of paraffin-embedded human spleen tissue. 1,primary Antibody was diluted at 1:200(4° overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200
Western Blot analysis of K-562 cell ,using primary antibody at 1:1000 dilution. Secondary antibody(catalog#:RS23920) was diluted at 1:10000