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ATP4B rabbit pAb
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ES10039
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ATP4B rabbit pAb
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 160-240
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 32kD
GeneID: 496
Human Swiss-Prot No: P51164
Cellular localization: Apical cell membrane ; Single-pass type II membrane protein . Cell membrane ; Single-pass type II membrane protein . Localized in the apical canalicular membrane of parietal cells. .
Background: The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008],