Synthesized peptide derived from human protein . at AA range: 800-880
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
113kD
GeneID:
495
Human Swiss-Prot No:
P20648
Cellular localization:
Apical cell membrane ; Multi-pass membrane protein . Localized in the apical canalicular membrane of parietal cells (PubMed:24188822). Localized in the apical canalicular membrane of parietal cells (PubMed:24188822). .
Background:
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008],
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