| Product name: | Recombinant Human NgR (C-6His) | 
								
								                                        
                                           | Description: | Recombinant Human Nogo-66 Receptor/Reticulon 4 Receptor is produced by our Mammalian expression system and the target gene encoding Cys27-Ser447 is expressed with a 6His tag at the C-terminus. | 
                                                                                
                                           | Accession: | Q9BZR6 | 
                                                                                
                                           | Molecular weight: | 46.32 KDa | 
                                                                                
                                           | Apparent molecular weight: | 60-90 KDa, reducing conditions | 
                                                                                
                                           | Purity: | Greater than 95% as determined by reducing SDS-PAGE. | 
                                                                                
                                           | Endotoxin: | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. | 
                                                                                
                                           | Redissolve: | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. | 
                                                                                
                                           | Storage: | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. | 
                                                                                
                                           | Delivery condition: | The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below. | 
                                                                                
                                           | Background: | Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions. |