Product name: | P38 (1G1) Mouse mAb |
Reactivity: | Human, Mouse, Rat |
Alternative Names: | MAP kinase p38 alpha, p38 MAP kinase, CSBP , RK, MAPK 14 antibody |
Source: | Mouse |
Dilutions: | IHC 1:100-200 |
Immunogen: | Synthetic Peptide |
Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Concentration: | 1mg/mL |
Observed Band: | 42kDa |
GeneID: | 1432 |
Human Swiss-Prot No: | Q16539 |
Cellular localization: | Cytoplasm,Nucleus |
Background: | p38 MAP kinase (MAPK) is the mammalian orthologue of the yeast HOG kinase that participates in a signaling cascade controlling cellular responses to cytokines and stress. Isoforms p38α, β, γ and δ have been identified. p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharide (LPS), UV light, and growth factors. |