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Smad3 (4C9) Mouse mAb
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EM1315
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Smad3 (4C9) Mouse mAb
Reactivity: Human, Rat, Mouse
Alternative Names: hMAD3 antibody, HSPC193 antibody, LDS1C antibody, MADH3 antibody, JV15 2 antibody
Source: Mouse
Dilutions: WB  1:1,000-2,000     IHC 1:100-200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 52kDa
GeneID: 4088
Human Swiss-Prot No: P84022
Cellular localization: Cytoplasm, Nucleus
Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.